The Science Behind CA-62

The CA-62 biomarker represents a breakthrough in early cancer detection science. Validated in over 5,000 clinical samples and published in peer-reviewed journals.

What is the CA-62 Biomarker?

CA-62 is a family of low-weight membrane transport N-glycoproteins that appear uniquely on the surface of poorly differentiated cells — including embryonic, stem, and cancer cells — during malignant transformation.

When epithelial cells undergo malignant transformation, they transform into pluripotent stem cells. The CA-62 glycoprotein appears on the surface of these cancer cells, enters the intracellular space, and then circulates in the bloodstream where it can be detected and quantified.

Critically, CA-62 levels are highest during the early stages of cancer, making it an exceptional tool for early detection — precisely when treatment is most effective.

Key Distinction: Unlike many cancer biomarkers that are organ-specific (e.g., PSA for prostate, CA-125 for ovarian), CA-62 is a universal epithelial cancer marker — it detects a wide range of epithelial carcinomas from a single blood test.

CA-62 molecular biomarker visualization

Pilot Study Results

A prospective pilot study of 1,005 asymptomatic participants demonstrated exceptional early cancer detection capabilities.

1,005
Total Participants
Asymptomatic, age 45+
88–94%
Sensitivity
At 95% specificity
100%
Negative Predictive Value
Zero false negatives*
11/11
Cancers Detected
Perfect detection record*

Cancer Types Detected

B-cell lymphoma
Sigmoid carcinoma
Choroidal melanoma
Acute leukemia
Renal cell carcinoma
Breast cancer (2 cases)
Prostate cancer (2 cases)
Endometrial carcinoma (2 cases)

Pre-Cancerous & Inflammatory Conditions

Adenomatous polyps(Pre-cancerous)
9 cases
Prostate adenoma(Pre-cancerous)
1 case
Acute GI disorders(Inflammatory)
5 cases
Hepatobiliary conditions(Inflammatory)
4 cases
Immune-mediated lung diseases(Sarcoidosis-type)
3 cases

*Pilot study of 1,005 participants. Results may vary in larger populations. CA-62 is a wellness test, not FDA-approved for diagnostic use.

Early-Stage Sensitivity: CA-62 vs. Galleri

The most important metric for a cancer screening test is its ability to detect cancer in its earliest, most treatable stages.

>90%
Early-Stage Sensitivity

Demonstrated sensitivity exceeding 90% for Stage I and II epithelial cancers, including carcinoma in situ (Stage 0).

Highest when it matters most
27.5%
Early-Stage Sensitivity

Published clinical data shows Galleri's sensitivity for Stage I–II cancers ranges from approximately 27.5% to 37.3%.

Source: The Lancet, 2024

Why this matters: A cancer screening test must have high sensitivity for early-stage disease, where intervention is most likely to lead to a cure. A test that detects only 27.5% of early-stage cancers will miss the majority of cases when they are most treatable.Read The Lancet analysis

Experience the Science for Yourself

Order your CA-62 test today and benefit from the most sensitive early-stage cancer screening available.

Order Your Test — $300